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PLBL2 (Phospholipase B-Like 2) ELISA Kit – CHO (Chinese Hamster Ovary) Host Cell Protein
Catalog #
E-65PLB
Product Size
1
plate
The PLBL2 (Phospholipase B-Like 2) ELISA Kit – CHO (Chinese Hamster Ovary) Host Cell Protein is a highly sensitive immunoassay designed to detect PLBL2, a high-risk host cell protein (HCP) known for its immunogenic potential and its role in polysorbate degradation and formulation instability in monoclonal antibody (mAb) production. Even trace amounts of PLBL2 can compromise product safety and stability, making its detection and removal critical.
- Target: Phospholipase B-Like 2 (PLBL2)
- Species Reactivity: Hamster (CHO)
- Detection Range: 20 ng/mL – 0.3125 ng/mL
- Sensitivity: 0.080 ng/mL
- Assay Time: ~170 minutes
- Sample Type: Tissue culture fluids
- Storage: 2–8°C
- Shelf Life: 1 year
- Application: ELISA
This kit supports biopharmaceutical safety, HCP monitoring, and robust bioprocess development, and is backed by recent literature highlighting its importance in mAb purification workflows
| Antibody Type | ELISA |
|---|---|
| Target Species | Hamster |
| Specificity/Target | PLBL2 |
| Size | 1 |
| Detection Range | 20 ng/mL - 0.3125 ng/ml |
| Sensitivity | 0.080 ng/ml |
| Assay Time | 170 minutes |
| Sample Type | Tissue Culture Fluids |
| Origin | USA |
| Shelf Life | 1 year |
| Storage | 2-8C |
Data Sheet
SDS
, , , , , , , , , & (2024). Buffer System Improves the Removal of Host Cell Protein Impurities in Monoclonal Antibody Purification. Biotechnology and Bioengineering, 1–12. https://doi.org/10.1002/bit.28844
Falkenberg H, Waldera-Lupa DM, Vanderlaan M, Schwab T, Krapfenbauer K, Studts JM, Flad T, Waerner T. Mass spectrometric evaluation of upstream and downstream process influences on host cell protein patterns in biopharmaceutical products. Biotechnol Prog. 2019 May;35(3):e2788. doi: 10.1002/btpr.2788. Epub 2019 Mar 6. PMID: 30767403.
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