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anti-Hamster (CHO) Phospholipase B-Like 2 (PLBL2) - Affinity Purified
This polyclonal antibody is designed for the specific detection of Phospholipase B-like 2 (PLBL2) in Chinese Hamster Ovary (CHO) cells. PLBL2 is a host cell protein (HCP) known to interfere with monoclonal antibody purification and stability. Produced in goat and affinity-purified for high specificity, this antibody is ideal for ELISA and Western blot applications in bioprocessing and impurity profiling.
- Host Species: Goat
- Target: Phospholipase B-like 2 (CHO)
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, Western Blot
- Format: Lyophilized, Unconjugated
- Buffer: Phosphate buffered saline (PBS), pH 7.2
- Purity: Antigen Affinity Purified
- Catalog #: GPLB-65ALY-Z
- Origin: USA
| Antibody Type | Primary Antibody |
|---|---|
| Host | Goat |
| Target Species | Hamster |
| Specificity/Target | PLBL2 |
| Size | 0.5 |
| Clonality | Polyclonal |
| Type | Unconjugated |
| Isotype | IgG |
| Origin | USA |
| Shelf Life | 1 year |
| Format | Lyophilized |
| Buffer | Phosphate buffered saline (PBS), pH 7.2 with Stabilizer |
| Storage | 2 - 8 C |
| Application | ELISA, WB |
| Purity | Antigen Affinity Purified |
Dolan, M. E., Wang, L., Tedeschi, A., Wang, Y., Barton, C., Oppenheim, S. F., & Zhou, Z. S. (2025). Elucidation of proteoforms of Chinese hamster ovary (CHO) phospholipase B‐like 2 (PLBL2) captured from a monoclonal antibody. Biotechnology and Bioengineering, 1–14. https://doi.org/10.1002/bit.70104
Dolan ME, Sadiki A, Wang LL, Wang Y, Barton C, Oppenheim SF, Zhou ZS. First site-specific conjugation method for native goat IgG antibodies via glycan remodeling at the conserved Fc region. Antib Ther. 2024 Jul 10;7(3):233-248. doi: 10.1093/abt/tbae014. PMID: 39262442; PMCID: PMC11384149.
Dolan ME, Tedeschi A, Oppenheim SF, and Zhou ZS. Site-Specific Immobilization of Antibodies as a Platform Approach to Enable the Targeted Capture and Effective Removal of Problematic Host Cell Proteins (HCPs) from Complex Bioprocess Streams, Even at Sub-ppm Levels: Chinese Hamster Ovary (CHO) Phospholipase B-Like 2 (PLBL2) Northeastern University Department of Chemistry and Chemical Biology, Takeda Development Center Americas Inc December 09, 2024

