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Transforming Growth Factor Beta-1 ELISA Kit – CHO (Chinese Hamster Ovary) Host Cell Protein
The Transforming Growth Factor Beta-1 (Host Cell Protein) ELISA Kit – CHO (Chinese Hamster Ovary) is a highly sensitive immunoassay designed to detect Transforming Growth Factor Beta-1 (TGF-β1), a multifunctional cytokine involved in cell growth regulation, immune signaling, differentiation, and apoptosis. As a residual host cell protein released from CHO cells during biologics manufacturing, TGF-β1 may pose risks due to its potent biological activity and potential impact on product safety if not adequately removed during downstream purification.
This assay enables precise quantification of residual TGF-β1 in bioprocess samples and supports manufacturers seeking greater visibility into biologically active host cell protein contaminants.
- Target: Transforming Growth Factor Beta-1 (TGF-β1)
- Species Reactivity: Hamster (CHO)
- Detection Range: 20 ng/mL – 0.3125 ng/mL
- Sensitivity: 0.138 ng/mL
- Assay Time: ~170 minutes
- Sample Type: Tissue culture fluids
- Storage: 2–8°C
- Shelf Life: 1 year
- Application: ELISA
This kit is ideal for HCP monitoring, bioprocess development, and biopharmaceutical quality control, helping manufacturers better detect biologically active residual proteins that may impact product safety, regulatory compliance, and therapeutic consistency.
| Antibody Type | ELISA |
|---|---|
| Target Species | Hamster |
| Specificity/Target | Transforming Growth Factor Beta-1 |
| Size | 1 |
| Detection Range | 20 ng/mL - 0.3125 ng/ml |
| Sensitivity | 0.138 ng/ml |
| Assay Time | 170 minutes |
| Type | Tissue Culture Fluids |
| Sample Type | Tissue Culture Fluids |
| Origin | USA |
| Shelf Life | 1 year |
| Storage | 2-8C |
| Application | ELISA |
, , , , , , , , , & (2024). Buffer System Improves the Removal of Host Cell Protein Impurities in Monoclonal Antibody Purification. Biotechnology and Bioengineering, 1–12. https://doi.org/10.1002/bit.28844
Falkenberg H, Waldera-Lupa DM, Vanderlaan M, Schwab T, Krapfenbauer K, Studts JM, Flad T, Waerner T. Mass spectrometric evaluation of upstream and downstream process influences on host cell protein patterns in biopharmaceutical products. Biotechnol Prog. 2019 May;35(3):e2788. doi: 10.1002/btpr.2788. Epub 2019 Mar 6. PMID: 30767403.

