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Hamster (CHO) Cathepsin Z - Recombinant
Catalog #
AG65-0441-LY
Product Size
0.025
mg
Cathepsin Z is a lysosomal cysteine protease with both carboxypeptidase and non-proteolytic functions, including roles in immune response and cell adhesion. Produced by host cells like Chinese Hamster Ovary (CHO) cells in biopharmaceutical manufacturing, it's considered a Host Cell Protein (HCP) impurity.
Residual Cathepsin Z can potentially degrade recombinant therapeutic proteins during purification and storage, impacting their quality, efficacy, and safety.
Studies show higher levels of CTSZ are associated with tumor progression and metastasis, highlighting the need for its removal during bioprocessing. Careful monitoring and removal of Cathepsin Z, and other HCPs, are thus critical to ensure product quality and patient safety.
| Antibody Type | Antigen |
|---|---|
| Host | Recombinant |
| Target Species | Hamster |
| Specificity/Target | Cathepsin Z |
| Size | 0.025 |
| Type | Purified Protein |
| Sample Type | Control |
| Origin | USA |
| Shelf Life | 1 year |
| Format | Lyophilized |
| Buffer | PBS, pH 7.2 |
| Storage | 2 -8C before reconstitution |
| Application | ELISA |
| Purity | Purified Protein |
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