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Hamster (CHO) Legumain - Recombinant
Catalog #
AG65-0423-LY
Product Size
0.025
mg
Legumain is a host cell protein (HCP) generated by CHO cells during production of biotherapeutics. This process-related impurity accumulates in the extracellular space as it is released from dead CHO cells and secreted from viable cells during cell culture. Legumain, a lysosomal protease, cleaves the asparaginyl and aspartyl bonds of therapeutic monoclonal antibodies, thus compromising their integrity, stability, and efficacy.
Purified recombinant CHO Legumain (LGMN) expressed in CHO-S cells. Contains a 6xHIS tag.
| Antibody Type | Antigen |
|---|---|
| Host | Recombinant |
| Target Species | Hamster |
| Specificity/Target | Legumain |
| Size | 0.025 |
| Origin | USA |
| Shelf Life | 1 year |
| Format | Lyophilized |
| Buffer | Phosphate buffered saline (PBS), pH 7.2 |
| Storage | 2 -8C for short term, aliquot and store at -80C for >10 days. |
| Application | ELISA, WB |
| Purity | Purified Protein |
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