ELISA Kits

Mouse C3 ELISA Kit

Catalog #
E-90C3
Product Size
1.0 plate
$422.27

Complement C3 is a protein that plays a crucial role in the immune system as part of the complement system. The complement system is a complex network of proteins that work together to enhance the immune response against pathogens such as bacteria and viruses. Complement C3 is one of the central components of this system.

When the complement system is activated, C3 is cleaved into two fragments: C3a and C3b. C3b plays a key role in opsonization, a process in which pathogens are marked for destruction by phagocytic cells, such as macrophages. Additionally, C3b participates in the formation of the membrane attack complex (MAC), which can directly lyse and kill certain pathogens.

The complement system is an essential part of the immune defense mechanism, contributing to the body's ability to recognize and eliminate foreign invaders. Dysregulation of the complement system has been associated with various autoimmune diseases and inflammatory conditions.

More Information
Antibody Type ELISA
Host Goat
Target Species Mouse
Specificity/Target C3
Size 1.0
Detection Range 3.125 ng/ml - 200 ng/ml
Sensitivity 1.379 ng/ml
Assay Time 50 min.
Sample Type Plasma, Serum
Storage 2-8C
Data Sheet
Mouse_C3_V4.0.pdf
SDS
SDS_E-90C3_051222.pdf

Mouse C3 ELISA Kit

Yoon H, Schaubeck M, Lagkouvardos I, et al. Increased Pancreatic Protease Activity in Response to Antibiotics Impairs Gut Barrier and Triggers Colitis. Cell Mol Gastroenterol Hepatol. 2018;6(3):370-388.e3. Published 2018 May 29. doi:10.1016/j.jcmgh.2018.05.008

Yan Q et al. Prevention of Immune Nephritis by the Small Molecular Weight Immunomodulator Iguratimod in MRL/lpr Mice. Ed. Jean Kanellopoulos. PLoS ONE 9.10 (2014): e108273. PMC. Web. 26 June 2017.

Yan Q, et al. (2014) Prevention of Immune Nephritis by the Small Molecular Weight Immunomodulator Iguratimod in MRL/lpr Mice. PLoS ONE 9(10): e108273. doi:10.1371/journal.pone.0108273

Strait RT, et al. MHC class I–specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice www.jem.org/cgi/doi/10.1084/jem.20110159

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