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Bovine Haptoglobin ELISA Kit
The E-10HPT kit from ICL is a rapid and reliable ELISA assay designed for the quantitative measurement of haptoglobin in bovine plasma or serum samples. Haptoglobin is an acute phase protein that increases in response to inflammation, infection, or tissue damage, making it a valuable biomarker for monitoring bovine health.
Key Features:
- Target: Bovine Haptoglobin
- Format: ELISA (Enzyme-Linked Immunosorbent Assay)
- Detection Range: 15.6 ng/ml – 1000 ng/ml
- Sensitivity: ~6.26 ng/ml
- Assay Time: ~40 minutes
- Sample Types: Plasma, Serum
- Storage: 2–8°C
- Applications: Research use only (not for diagnostic or therapeutic use)
Use Cases:
- Monitoring acute phase response in cattle
- Evaluating inflammation or infection
- Supporting veterinary research in bovine health and disease
| Antibody Type | ELISA |
|---|---|
| Host | Goat |
| Target Species | Bovine |
| Specificity/Target | Haptoglobin |
| Size | 1.0 |
| Detection Range | 15.6 ng/ml- 1000 ng/ml |
| Sensitivity | 6.258 ng/ml |
| Assay Time | 40 min. |
| Sample Type | Plasma, Serum |
| Storage | 2-8C |
Publications citing ICL's Bovine Haptoglobin ELISA Kit
Okagawa, T., Nojiri, N., Yoshida-Furihata, H., Nao, N., Tominaga, M., Kohara, J., Gondaira, S., Higuchi, H., Takeda, Y., Ogawa, H., Yamada, S., Murakami, K., Suzuki, Y., Takai, S., Maezawa, M., Inokuma, H., Shimizu, K., Inoshima, Y., Usui, T., ... Konnai, S. (2025). Performance evaluation of an improved RAISING method for clonality analysis of bovine leukemia virus-infected cells: A collaborative study in Japan. Journal of Veterinary Medical Science, 87(5), 551–558. https://doi.org/10.1292/jvms.25-0031
Henderson JA, Genther-Schroeder ON, Hansen SL, McGill JL. The impact of excess liver copper concentrations on response to a bovine respiratory disease challenge in lightweight beef-on-dairy crossbred steers. J Anim Sci. 2025 Jul 9:skaf218. doi: 10.1093/jas/skaf218. PMID: 40628646.
Maia Ribeiro, T. L., Grimes Francis, Becca. B., Ross, Cassidy. R., Delver, Justin. J., Francis, F. L., Heldt, J. S., … Smith, Z. K. (2024). Evaluation of a phytogenic blend fed with monensin on post-weaning growth performance, health, and sera metabolite responses during the initial 56 d feedlot receiving period in steer calves. Acta Agriculturae Scandinavica, Section A — Animal Science, 74(1), 18–26. https://doi.org/10.1080/09064702.2024.2402696
Kim, J.; Kim, D.; Noh, H.; Hong, L.; Chun, E.; Kim, E.; Ro, Y.; Choi, W. Analysis of Acute Phase Response Using Acute Phase Proteins Following Simultaneous Vaccination of Lumpy Skin Disease and Foot-and-Mouth Disease. Vaccines 2024, 12, 556. https://doi.org/10.3390/vaccines12050556
Ceja G, Boerman JP, Neves RC, Jorgensen MW, Johnson JS. l-Glutamine supplementation reduces gastrointestinal permeability and biomarkers of physiological stress in preweaning Holstein heifer calves. J Dairy Sci. 2023;106(12):9663-9676. doi:10.3168/jds.2023-23334
Daddam JR, Daniel D, Kra G, et al. Plant polyphenol extract supplementation affects performance, welfare, and the Nrf2-oxidative stress response in adipose tissue of heat-stressed dairy cows. J Dairy Sci. 2023;106(12):9807-9821. doi:10.3168/jds.2023-23549
Chitko-McKown CG, Bennett GL, Kuehn LA, et al. Cytokine and Haptoglobin Profiles From Shipping Through Sickness and Recovery in Metaphylaxis- or Un-Treated Cattle. Front Vet Sci. 2021;8:611927. Published 2021 Mar 19. doi:10.3389/fvets.2021.611927
Briggs NG, Silva BC, Godoi LA, Schoonmaker JP. Effect of aspirin to intentionally induce leaky gut on performance, inflammation, and carcass characteristics of feedlot cattle. J Anim Sci. 2021;99(11):skab328. doi:10.1093/jas/skab328
Kaufman JD, Seidler Y, Bailey HR, et al. A postbiotic from Aspergillus oryzae attenuates the impact of heat stress in ectothermic and endothermic organisms. Sci Rep. 2021;11(1):6407. Published 2021 Mar 19. doi:10.1038/s41598-021-85707-3
Kim, Daehyun et al. Effect of Foot-and-Mouth Disease Vaccination on Acute Phase Immune Response and Anovulation in Hanwoo (Bos taurus coreanae). Vaccines vol. 9,5 419. 22 Apr. 2021, doi:10.3390/vaccines9050419
Briggs NG, Brennan KM, Funnell BJ, Nicholls GT, Schoonmaker JP. Use of aspirin to intentionally induce gastrointestinal tract barrier dysfunction in feedlot cattle. J Anim Sci. 2020;98(9):skaa264. doi:10.1093/jas/skaa264
Burdick Sanchez NC, Carroll JA, Broadway PR, Edrington TS, Yoon I, Belknap CR. Some aspects of the acute phase immune response to a lipopolysaccharide (LPS) challenge are mitigated by supplementation with a Saccharomyces cerevisiae fermentation product in weaned beef calves. Transl Anim Sci. 2020;4(3):txaa156. Published 2020 Aug 24. doi:10.1093/tas/txaa156
Zachut M, Kra G, Nemes-Navon N, et al. Seasonal heat load is more potent than the degree of body weight loss in dysregulating immune function by reducing white blood cell populations and increasing inflammation in Holstein dairy cows. J Dairy Sci. 2020;103(11):10809-10822. doi:10.3168/jds.2020-18547
Wickramasinghe, H. K. J. P. et al. Drinking water intake of newborn dairy calves and its effects on feed intake, growth performance, health status, and nutrient digestibility 377J. Dairy Sci. 102:377–387https://doi.org/10.3168/jds.2018-15579
Ball JJ, Kegley EB, Lawrence TE, Roberts SL, Powell JG, Richeson JT. Zinc injection as a novel castration method in beef bulls: effects on performance, behavior, and testosterone and haptoglobin concentration. J Anim Sci. 2018;96(3):890-901. doi:10.1093/jas/skx039
Roberts SL, Powell JG, Hughes HD, Richeson JT. Effect of castration method and analgesia on inflammation, behavior, growth performance, and carcass traits in feedlot cattle. J Anim Sci. 2018;96(1):66-75. doi:10.1093/jas/skx022
Lai, I-Hsiang et al. Neutrophils as One of the Major Haptoglobin Sources in Mastitis Affected Milk. Veterinary Research 40.3 (2009): 17. PMC. Web. 13 Sept. 2017.
Lüttgenau J, Lingemann B, Wellnitz O, et al. Repeated intrauterine infusions of lipopolysaccharide alter gene expression and lifespan of the bovine corpus luteum. J Dairy Sci. 2016;99(8):6639-6653. doi:10.3168/jds.2015-10806
Lüttgenau J, Wellnitz O, Kradolfer D, et al. Intramammary lipopolysaccharide infusion alters gene expression but does not induce lysis of the bovine corpus luteum. J Dairy Sci. 2016;99(5):4018-4031. doi:10.3168/jds.2015-10641
Kvidera SK, Dickson MJ, Abuajamieh M, et al. Intentionally induced intestinal barrier dysfunction causes inflammation, affects metabolism, and reduces productivity in lactating Holstein cows. J Dairy Sci. 2017;100(5):4113-4127. doi:10.3168/jds.2016-12349
Nonnecke BJ et al. Acute phase response elicited by experimental bovine diarrhea virus (BVDV) infection is associated with decreased vitamin D and E status of vitamin-replete preruminant calves. J Dairy Sci. 2014 Sep;97(9):5566-79. doi: 10.3168/jds.2014-8293. Epub 2014 Jul 11.
Krueger LA, Beitz DC, Onda K, et al. Effects of d-α-tocopherol and dietary energy on growth and health of preruminant dairy calves. J Dairy Sci. 2014;97(6):3715-3727. doi:10.3168/jds.2013-7315
Wolfs TG, Kramer BW, Thuijls G, et al. Chorioamnionitis-induced fetal gut injury is mediated by direct gut exposure of inflammatory mediators or by lung inflammation. Am J Physiol Gastrointest Liver Physiol. 2014;306(5):G382-G393. doi:10.1152/ajpgi.00260.2013
Richeson JT et al. Weaning management of newly received beef calves with or without continuous exposure to a persistently infected bovine viral diarrhea virus pen mate: Effects on rectal temperature and serum proinflammatory cytokine and haptoglobin concentrations J Anim Sci. 2013 Mar;91(3):1400-8. doi: 10.2527/jas.2011-4875. Epub 2013 Jan 23.
Maden M, Ozturk AS, Bulbul A, Avci GE, Yazar E. Acute-phase proteins, oxidative stress and enzyme activities of blood serum and peritoneal fluid in cattle with abomasal displacement. J Vet Intern Med. 2012;26(6):1470-1475. doi:10.1111/j.1939-1676.2012.01018.x
Dehghan-banadaky M et al. Effects of Complete Vitamin and MineralSupplementation in Full Potential All-milk Diets onGrowth and Health of Holstein Bull Calves Animal Industry Report: AS661, ASL R2968. Available at: http://lib.dr.iastate.edu/ans_air/vol661/iss1/31

