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anti-Hamster (CHO) Phospholipase B-Like 2 (PLBL2) - Monoclonal
This monoclonal antibody is designed for the specific detection of Phospholipase B-like 2 (PLBL2) in Chinese Hamster Ovary (CHO) cells. PLBL2 is a host cell protein (HCP) known to interfere with monoclonal antibody purification and stability. Produced in mouse and purified for high specificity, this antibody is ideal for ELISA and Western blot applications in bioprocessing and impurity profiling.
- Host Species: Mouse
- Target: Phospholipase B-like 2 (CHO)
- Clonality: Monoclonal
- Clone: 4D5
- Isotype: IgG1
- Applications: ELISA, Western Blot
- Format: Lyophilized, Purified Protein
- Buffer: Phosphate buffered saline (PBS), pH 7.2
- Purity: Purified Protein
- Catalog #: MPLB-65ALY-4D5
- Origin: USA
- Shelf Life: 1 year
| Antibody Type | Primary Antibody |
|---|---|
| Host | Mouse |
| Target Species | Hamster |
| Specificity/Target | PLBL2 |
| Size | 0.5 |
| Clonality | Monoclonal |
| Type | Purified Protein |
| Sample Type | Control |
| Isotype | IgG1 |
| Clone | 4D5 |
| Origin | USA |
| Shelf Life | 1 year |
| Format | Lyophilized |
| Buffer | Phosphate buffered saline (PBS) |
| Storage | 2-8C prior to reconstitution |
| Purity | Purified Protein |
Dolan, M. E., Wang, L., Tedeschi, A., Wang, Y., Barton, C., Oppenheim, S. F., & Zhou, Z. S. (2025). Elucidation of proteoforms of Chinese hamster ovary (CHO) phospholipase B‐like 2 (PLBL2) captured from a monoclonal antibody. Biotechnology and Bioengineering, 1–14. https://doi.org/10.1002/bit.70104
Dolan ME, Tedeschi A, Oppenheim SF, and Zhou ZS. Site-Specific Immobilization of Antibodies as a Platform Approach to Enable the Targeted Capture and Effective Removal of Problematic Host Cell Proteins (HCPs) from Complex Bioprocess Streams, Even at Sub-ppm Levels: Chinese Hamster Ovary (CHO) Phospholipase B-Like 2 (PLBL2) Northeastern University Department of Chemistry and Chemical Biology, Takeda Development Center Americas Inc December 09, 2024

