Research Reagents

anti-C-Myc Antibody (Rabbit) - Affinity Purified

Catalog #
RMYC-45A
Product Size
1.0 mg
$766.00

The C-MYC tag is a short peptide sequence derived from the c-myc gene. Researchers use this tag to label and detect proteins in molecular biology and cell biology studies. Attaching the c-myc tag to a protein of interest allows for easy detection, purification, and tracking of that protein within cells or experimental systems.

More Information
Antibody Type Primary Antibody
Reactivity C-Myc Tag
Host Rabbit
Specificity/Target C-Myc tag
Size 1.0
Clonality Polyclonal
Type Unconjugated
Isotype IgG
Origin USA
Shelf Life 2 years
Format Liquid
Buffer Phospate buffered saline, pH 7.2
Preservative 0.09% sodium azide
Storage 2-8C
Application ELISA
Purity Antigen Affinity Purified
Data Sheet
PP_RMYC-45A.pdf
SDS
ICL_SDS_RMYC-45A_and_Z.pdf

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Chen YJ, Knupp J, Arunagiri A, Haataja L, Arvan P, Tsai B. PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones. Nat Commun. 2021;12(1):5991. Published 2021 Oct 13. doi:10.1038/s41467-021-26225-8

Haataja L, Arunagiri A, Hassan A, et al. Distinct states of proinsulin misfolding in MIDY. Cell Mol Life Sci. 2021;78(16):6017-6031. doi:10.1007/s00018-021-03871-1

Sun J. et al. Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth. Diabetes. 2020 May;69(5):954-964. doi: 10.2337/db19-1106. Epub 2020 Mar 5. PMID: 32139596; PMCID: PMC7171958.

Chen Y. et al. Reticulon protects the integrity of the ER membrane during ER escape of large macromolecular protein complexes J Cell Biol (2020) 219 (2): e201908182. https://doi.org/10.1083/jcb.201908182

Cunningham CN, Williams JM, Knupp J, Arunagiri A, Arvan P, Tsai B. Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates. Mol Cell. 2019;75(3):442-456.e4. doi:10.1016/j.molcel.2019.05.011

Cunningham CN et al. Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel with Restoration of Wild Type Insulin Secretion. Diabetes. 2016 Dec 27. pii: db161338. doi: 10.2337/db16-1338. [Epub ahead of print] Pubmed: 28028074

He K et al. PDI reductase acts on Akita mutant proinsulin to initiate retrotranslocation along the Hrd1/Sel1L-p97 axis. Mol. Biol. Cell October 1, 2015 vol. 26 no. 19 3413-3423

Wright J et al. Dominant protein interactions that influence the pathogenesis of conformational diseases J Clin Invest. 2013;123(7):3124-3134. doi:10.1172/JCI67260.

Liu M et al. Impaired Cleavage of Preproinsulin Signal Peptide Linked to Autosomal-Dominant Diabetes Diabetes Apr 2012, 61 (4) 828-837; DOI: 10.2337/db11-0878

Kalkan T et al. Tumor Necrosis Factor-Receptor–associated Factor-4 Is a Positive Regulator of Transforming Growth Factor-β Signaling That Affects Neural Crest Formation Mol. Biol. Cell July 15, 2009 vol. 20 no. 14 3436-3450

Xu B, Yang WH, Gerin I, Hu CD, Hammer GD, Koenig RJ. Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis. Mol Cell Biol. 2009;29(7):1719-1734. doi:10.1128/MCB.01010-08

Jin Z, Zhang J, Klar A, et al. Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina. Development. 2003;130(6):1037-1048. doi:10.1242/dev.00326

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